General Cell Lines and Cell Cultures
Biochain Institute Inc Frozen Tissue Section - Alzheimer's Disease: Brain: Occipital Lobe, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Abeomics Nrf2 Reporter Mcf7 Cell Line
The Nrf2 Leeporter Luciferase Reporter cell line is a stably transfected MCF7 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the antioxidant response element (ARE). ARE is known to regulate expression and induction of various detoxifying enzyme genes in response to antioxidants and xenobiotics, and is primarily regulated by the Keap1-Nrf2 pathway in which induction and nuclear translocation of Nrf2 mediated by antioxidants and xenobiotics results in the binding of Nrf2 to ARE leading to the expression of defensive genes. Cell line application: (1) Monitor the Nrf2 induction activity, and (2) Screen for activators or inhibitors of the Nrf2 signaling pathway. .
Eurofins Discoverx Ready-to-Assay NK1 Tachykinin Receptor Frozen Cells, 2 Vials of Cells. (HTS080RTA)
The Ready-to-Assay NK1 Tachykinin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. tachykinins) based activation of TACR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses TACR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of TACR1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Biotium PAX8 (Renal Cell Marker)(PAX8/2774R), CF568 conjugate, 0.1mg/mL
Recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors. Primary antibodies are available purified, or with a
ATCC Pfizer Pneumococcal polysaccharide powder Type 8 (d8) 2mg
Purified pneumococcal polysaccharide type 8 is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 8 can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Biochain Institute Inc Matched Pair - DNA - Human Primary Tumor and Normal Tissue: Breast, 2x10 ug/PK
BioChain's human DNA matched pair products include: Primary Pair (PP), Primary and Metastasis Pair (PM). PP consists of DNA prepared from primary tumor and its adjacent normal tissue; PM consists of DNA prepared from primary tumor and corresponding ponding metastatic tumor. Genomic DNA in each pair is prepared from the same donor. This product line is designed foridentifying tumor-specific genes and tumor metastatic genes.
ATCC Monoclonal Antibody;Anti-SARS-CoV-2 Receptor; Binding Domain (RBD);protein, Clone 2TP1C3
Monoclonal antibody prepared against the Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein receptor binding domain. This product was purified from clone 2TP1C3 hybridoma supernatant by protein G affinity chromatography.
Biochain Institute Inc Frozen Tissue Section - Human Diabetic Diseased Tissue: Esophagus, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biolegend APC/Cyanine7 anti-human TCR Vd
APC/Cyanine7 anti-human TCR Vδ2 [B6]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 tests
iQ Biosciences Purified Cynomolgus Monkey CD8 T Cells, 2M cells/vial
High-quality, high-viability (> 90%) CD8 T cells purified from cynomolgus (cyno) monkey (or macaque) PBMCs by magnetic selection. Highly enriched (typically > 90%) post-selection purity achieved via magnetic isolation. Used for a wide variety of safety assessment and functional assays. All orders come with an iQ Certificate of Analysis.The following donor requests can be accommodated if inventory is available: - Single or multiple donors for a particular product (SKU). Indicate number of vials from each individual donor - Donor-matched PBMCs
Eurofins Discoverx PathHunter U2OS EphB4 Functional Assay, 2 vials. (93-0468C3)
The PathHunter U2OS EphB4 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphB4 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphB4 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC Quantitative Synthetic; Chlamydia trachomatis; LGV Type 3 DNA
Quantitative Synthetic Chlamydia trachomatis LGV Type 3 DNA can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load. Preparation includes fragments from MOMP, 16S rRNA, pmpH, and dnaB regions.
Eurofins Discoverx LPA2 (EDG4) Gq Calcium Signaling Cell-Based Assay Kit (CHO-K1)
The LPA2 (EDG4) Gq Stable Cell Line Calcium Signaling Assay (CHO-K1) contains a stable clonal cell line used to measure EDG4 (GPCR) activation via an increase in intracellular calcium. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Canine GPR91 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Canine GPR91 β-Arrestin Stable Cell Pool Assay (CHO-K1) contains a stable engineered cell pool used to measure canine GPR91 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell pool vials, all required culture reagents for maintaining the cells in continuous culture, and detection reagents for running the assay.
Eurofins Discoverx GNRHR Gq Calcium Signaling Cell-Based Assay Kit (CHO-K1)
The GNRHR Gq Stable Cell Line Calcium Signaling Assay (CHO-K1) contains a stable clonal cell line used to measure GNRHR (GPCR) activation via an increase in intracellular calcium. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.